TY  - THES
TY  - BOOK
T1  - Seroprevalence of Johne’s disease among deer livestock in UPM Deer Farm (PPP UPM) : prelimanary study
A1  - Shivnraj Sundar,
LA  - English
UL  - http://discoverylib.upm.edu.my/discovery/Record/598526
AB  - Johne’s disease (also known as paratuberculosis) caused by Mycobacterium avium subspecies. paratuberculosis (MAP) is an underdiagnosed bacterial disease associated with gastrointestinal systems of domestic and wild ruminants, causing significant economic losses through decreased productivity, low fertility and mortality with worldwide occurrence. It is known to affect the animal with a chronic irreversible wasting gastro-enteric disease featured by a long incubation period and a lifelong persistent infection. Despite extensive published seroprevalence studies on MAP in ruminant livestock including deer and to date, no seroprevalence data on MAP infection among deer in Malaysia has been reported or recorded. Therefore this preliminary study was conducted to determine the seroprevalence and risk factors associated with MAP among deer (Cervus timorensis) livestock at the UPM Deer Farm. A total of ninety-two samples were sourced from UPM Deer Farm comprising thirty-six serum samples collected in 2023 (new herd) and an additional fifty-six archived samples from 2017 (old herd) were included in this study. All the samples were screened using a commercial using ID Screen (PARAS Ver0516, ID.VET, France) indirect ELISA screening test to detect serum antibody directed against MAP. The International Business Machine (IBM) Statistical Package was used to perform statistical analysis and p-value was calculated using the Pearson Chi-square. The result of this study has revealed an overall apparent prevalence of 2.2% (95% CI= 1.00 – 8.00) and a true prevalence of 1.3% (95% CI= -0.45 – 7.40) for MAP among deer. However, the univariable analysis revealed that age (χ2 = 3.655: p=0.161), gender (χ2 = 0.643: p=0.423) and herd group (χ2 = 1.314: p=0.252) of deer were not significantly associated (p>0.05) with seropositivity to MAP. To the best of our knowledge, this study is the first documented evidence of serum antibodies towards MAP among Cervus timorensis in Malaysia. Further studies are needed to isolate and characterise the strain of MAP circulating among deer in Malaysia.
CN  - FPV 2023 51
ER  -