TY - GEN TY - GEN T1 - Mitochondria and the Heart T2 - Developments in Cardiovascular Medicine, A2 - Marín-García, José. A2 - Marín-García, José. LA - English PP - New York, NY PB - Springer US : Imprint: Springer YR - 2005 ED - 1st ed. 2005. UL - http://discoverylib.upm.edu.my/discovery/Record/978-0-387-25575-0 AB - The function of the heart is highly dependent on oxidative energy that is generated in mitochondria. Defects in mitochondrial structure and function can be found in association with cardiovascular diseases. Mitochondria and the Heart discusses the role that mitochondria plays in cardiovascular disease, including biogenesis and function of cardiac mitochondria during normal growth, development and aging. In addition, nonbioenergetic, biogenesis and degradation pathways are explored. Understanding these pathways and the effects that mitochondrial defects have in cardiac pathology is extremely important in establishing the diagnosis and treatment of mitochondrial-based cardiac diseases. José Marín-García is affiliated with The Molecular Cardiology and Neuromuscular Institute, Highland Park, New Jersey and the Department of Physiology & Biophysics, UMDNJ – Robert Wood Johnson Medical School, Piscataway, New Jersey. . OP - 400 CN - RC681-688.2 SN - 9780387255750 KW - Cardiology. ER -