TY - GEN TY - GEN T1 - Protein Misfolding, Aggregation and Conformational Diseases Part B: Molecular Mechanisms of Conformational Diseases T2 - Protein Reviews ; A2 - Uversky, Vladimir N. A2 - Uversky, Vladimir N. A2 - Fink, Anthony. A2 - Fink, Anthony. LA - English PP - New York, NY PB - Springer US : Imprint: Springer YR - 2007 ED - 1st ed. 2007. UL - http://discoverylib.upm.edu.my/discovery/Record/978-0-387-36534-3 AB - Protein Misfolding, Aggregation and Conformational Diseases, Part B: Molecular Mechanisms of Conformational Diseases, is a comprehensive volume providing a broad and detailed discussion of the relationships of protein misfolding and aggregation with the pathogenesis of numerous conformational diseases. While the Part A was dedicated to the description of the general mechanisms underlying protein misfolding, aggregation, and development of protein deposition disorders, this volume summarizes recent achievements in the understanding of the molecular mechanisms of conformational diseases. Research indicates that these mechanisms are highly diverse and range from the altered protein structure leading to the enhanced propensity for aggregation/deposition or the impaired functions and ending with changes in supra-molecular structures or posttranslational modification. Protein Misfolding, Aggregation and Conformational Diseases, Part B: Molecular Mechanisms of Conformational Diseases, is an ideal book for pharmaceutical scientists, molecular and cellular biologists, biochemists, immunologists, protein scientists, and biophysicists. OP - 538 CN - QR180-189.5 SN - 9780387365343 KW - Immunology. KW - Cell biology. KW - Cell Biology. ER -