Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics

Solvent systems are integral to drug development and pharmaceutical technology. This single topic encompasses numerous allied subjects running the gamut from recrystallization solvents to biorelevant media. The goal of this contribution to the AAPS Biotechnology: Pharmaceutical Aspects series is to...

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企业作者: SpringerLink (Online service)
其他作者: Augustijns, Patrick. (Editor, http://id.loc.gov/vocabulary/relators/edt), Brewster, Marcus. (Editor, http://id.loc.gov/vocabulary/relators/edt)
格式: 电子 电子书
语言:English
出版: New York, NY : Springer New York : Imprint: Springer, 2007.
版:1st ed. 2007.
丛编:Biotechnology: Pharmaceutical Aspects ; VI
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在线阅读:https://doi.org/10.1007/978-0-387-69154-1
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书本目录:
  • Principles of Solubility
  • Ionic Equilibria and the pH Dependence of Solubility
  • Solvent Systems for Crystallization and Polymorph Selection
  • Solubility Issues in Early Discovery and HTS
  • Practical Aspects of Solubility Determination in Pharmaceutical Preformulation
  • Biorelevant Dissolution Media
  • Selection of Solvent Systems for Membrane-, Cell- and Tissue-Based Permeability Assessment
  • The Use of Solubilizing Excipients and Approaches to Generate Toxicology Vehicles for Contemporary Drug Pipelines
  • Solubilizing Vehicles for Oral Formulation Development
  • Solubilizing Systems for Parenteral Formulation Development—Small Molecules
  • Aqueous Solubilizing Systems for Parenteral Formulation Development—Proteins
  • Non-Aqueous Systems for Formulation Development—Proteins
  • Pharmaceutical Solvents as Vehicles for Topical Dosage Forms
  • Pharmaceutical Solvents for Pulmonary Drug Delivery.