Neurochemical Aspects of Excitotoxicity
About 40% of central nervous system synapses use glutamate as the neurotransmitter. Over-stimulation of glutamate receptors produces neuronal injury or death by excitotoxicity, which is closely associated with neurochemical and neuropathological changes involved in acute neural trauma (stroke, spina...
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| Hlavní autoři: | , , |
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| Korporativní autor: | |
| Médium: | Elektronický zdroj E-kniha |
| Jazyk: | English |
| Vydáno: |
New York, NY :
Springer New York : Imprint: Springer,
2008.
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| Vydání: | 1st ed. 2008. |
| Témata: | |
| On-line přístup: | https://doi.org/10.1007/978-0-387-73023-3 |
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Obsah:
- Glutamate and Aspartate in Brain
- Excitatory Amino Acid Receptors in Brain
- Multiplicity of Glutamate Receptors in Brain
- Glutamate Transporters and Their Role in Brain
- Excitatory Amino Acid Receptors and Their Association with Neural Membrane Glycerophospholipid Metabolism
- Glutamate Receptors and Their Association with Other Neurochemical Parameters in Excitotoxicity
- Possible Mechanisms of Neural Injury Caused by Glutamate and Its Receptors
- Glutamate Receptors and Neurological Disorders
- Endogenous Antioxidant Mechanisms and Glutamate Neurotoxicity
- Glutamate Receptor Antagonists and the Treatment of Neurological Disorders
- Future Perspectives: New Strategies for Antagonism of Excitotoxicity, Oxidative Stress and Neuroinflammation in Neurodegenerative Diseases.



