Structural and Functional Organization of the Synapse

Synapses play a central role in the brain by mediating signal transmission between neurons. This book provides a fundamental description of the synapse by leading experts in the field. Each individual synapse carries out its numerous functions in a tiny space, thereby requiring an exquisite molecula...

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Bibliografiske detaljer
Institution som forfatter: SpringerLink (Online service)
Andre forfattere: Hell, Johannes W. (Editor, http://id.loc.gov/vocabulary/relators/edt), Ehlers, Michael D. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Format: Electronisk eBog
Sprog:English
Udgivet: New York, NY : Springer US : Imprint: Springer, 2008.
Udgivelse:1st ed. 2008.
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Online adgang:https://doi.org/10.1007/978-0-387-77232-5
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Indholdsfortegnelse:
  • Diversity in Synapse Structure and Composition
  • The Role of Glutamate Transporters in Synaptic Transmission
  • Structure and Function of Vertebrate and Invertebrate Active Zones
  • Neurotransmitter Release Machinery: Components of the Neuronal SNARE Complex and Their Function
  • The Molecular Machinery for Synaptic Vesicle Endocytosis
  • Initiation and Regulation of Synaptic Transmission by Presynaptic Calcium Channel Signaling Complexes
  • Adhesion Molecules at the Synapse
  • Dendritic Organelles for Postsynaptic Trafficking
  • Structure and Mechanism of Action of AMPA and Kainate Receptors
  • Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity
  • Structure and Function of the NMDA Receptor
  • Molecular Properties and Cell Biology of the NMDA Receptor
  • Surface Trafficking of Membrane Proteins at Excitatory and Inhibitory Synapses
  • Scaffold Proteins in the Postsynaptic Density
  • Ca2+ Signaling in Dendritic Spines
  • Postsynaptic Targeting of Protein Kinases and Phosphatases
  • Long-Term Potentiation
  • Homeostatic Synaptic Plasticity
  • Ubiquitin and Protein Degradation in Synapse Function
  • Signaling from Synapse to Nucleus
  • Molecular Organization of the Postsynaptic Membrane at Inhibitory Synapses
  • Acid-Sensing Ion Channels (ASICs) and pH in Synapse Physiology
  • Glia as Active Participants in the Development and Function of Synapses
  • Plasticity of Dentate Granule Cell Mossy Fiber Synapses: A Putative Mechanism of Limbic Epileptogenesis
  • Stroke – A Synaptic Perspective
  • and Pathological Pain.