Inflammation and Retinal Disease: Complement Biology and Pathology

Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene associations and links to other physiological pathways are emerging almost on a weekly base. Several promising clinical cand...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Awdur Corfforaethol: SpringerLink (Online service)
Awduron Eraill: Lambris, John D. (Golygydd, http://id.loc.gov/vocabulary/relators/edt), Adamis, Anthony P. (Golygydd, http://id.loc.gov/vocabulary/relators/edt)
Fformat: Electronig eLyfr
Iaith:English
Cyhoeddwyd: New York, NY : Springer New York : Imprint: Springer, 2010.
Rhifyn:1st ed. 2010.
Cyfres:Advances in Experimental Medicine and Biology, 703
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1007/978-1-4419-5635-4
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
Tabl Cynhwysion:
  • The Case for Complement and Inflammation in AMD: Open Questions
  • The Role of Complement in AMD
  • Multiple Interactions of Complement Factor H with Its Ligands in Solution: A Progress Report
  • Genetic Control of Complement Activation in Humans and Age Related Macular Degeneration
  • Bisretinoids of RPE Lipofuscin: Trigger for Complement Activation in Age-Related Macular Degeneration
  • The Role of the Classical Complement Cascade in Synapse Loss During Development and Glaucoma
  • A Role for Complement in Glaucoma?
  • The ATP-Binding Cassette Transporter ABCA4: Structural and Functional Properties and Role in Retinal Disease
  • Suppression of Drusen Formation by Compstatin, a Peptide Inhibitor of Complement C3 activation, on Cynomolgus Monkey with Early-Onset Macular Degeneration
  • A Targeted Inhibitor of the Complement Alternative Pathway Reduces RPE Injury and Angiogenesis in Models of Age-Related Macular Degeneration
  • Complement Depletion with Humanized Cobra Venom Factor in a Mouse Model of Age-Related Macular Degeneration.