Inflammation and Retinal Disease: Complement Biology and Pathology
Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene associations and links to other physiological pathways are emerging almost on a weekly base. Several promising clinical cand...
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| Autor Corporativo: | |
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| Outros Autores: | , |
| Formato: | Recurso Eletrônico livro eletrônico |
| Idioma: | English |
| Publicado em: |
New York, NY :
Springer New York : Imprint: Springer,
2010.
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| Edição: | 1st ed. 2010. |
| coleção: | Advances in Experimental Medicine and Biology,
703 |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1007/978-1-4419-5635-4 |
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Sumário:
- The Case for Complement and Inflammation in AMD: Open Questions
- The Role of Complement in AMD
- Multiple Interactions of Complement Factor H with Its Ligands in Solution: A Progress Report
- Genetic Control of Complement Activation in Humans and Age Related Macular Degeneration
- Bisretinoids of RPE Lipofuscin: Trigger for Complement Activation in Age-Related Macular Degeneration
- The Role of the Classical Complement Cascade in Synapse Loss During Development and Glaucoma
- A Role for Complement in Glaucoma?
- The ATP-Binding Cassette Transporter ABCA4: Structural and Functional Properties and Role in Retinal Disease
- Suppression of Drusen Formation by Compstatin, a Peptide Inhibitor of Complement C3 activation, on Cynomolgus Monkey with Early-Onset Macular Degeneration
- A Targeted Inhibitor of the Complement Alternative Pathway Reduces RPE Injury and Angiogenesis in Models of Age-Related Macular Degeneration
- Complement Depletion with Humanized Cobra Venom Factor in a Mouse Model of Age-Related Macular Degeneration.