Protein Deimination in Human Health and Disease

Deimination is a relatively new post-translational modification of proteins, whose recognition is ever-increasing. First linked to the pathology of rheumatoid arthritis (RA), deimination is a process by which selected positively charged arginine amino acids are converted to neutral citrulline amino...

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Xehetasun bibliografikoak
Erakunde egilea: SpringerLink (Online service)
Beste egile batzuk: Nicholas, Anthony P. (Argitaratzailea, http://id.loc.gov/vocabulary/relators/edt), Bhattacharya, Sanjoy K. (Argitaratzailea, http://id.loc.gov/vocabulary/relators/edt)
Formatua: Baliabide elektronikoa eBook
Hizkuntza:English
Argitaratua: New York, NY : Springer New York : Imprint: Springer, 2014.
Edizioa:1st ed. 2014.
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1007/978-1-4614-8317-5
Etiketak: Etiketa erantsi
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Aurkibidea:
  • Physiological pathways of PAD activity and citrullinated epitope generation
  • from citrullination to specific immunity and disease in rheumatoid arthritis
  • The role of citrullinated proteins in the pathophysiology of rheumatoid arthritis
  • Protein citrullination: the link between rheumatoid arthritis and periodontitis?
  • From genes and environment to anti-culture immunity in rheumatoid arthritis: The role of the lungs
  • Neutrophils and their contribution to autoimmunity in rheumatoid arthritis
  • Deimination in skin and regulation of PAD expression in keratinocytes
  • Importance of citrullination on hair protein molecular assembly during trichocytic differentiation
  • Deimination in the peripheral nervous system: A wallflower existence
  • Deimination in multiple sclerosis and experimental autoimmune encephalomyelitis
  • Protein hypercitrullination in CNS demyelinating disease reversed by PAD inhibition
  • Deimination in prion diseases
  • Deimination in Alzheimer's disease
  • Ongoing studies of deimination in neurodegenerative diseases using the F95 antibody
  • The role of protein deimination in epigenetics
  • Identifying citrullination sites by mass spectroscopy
  • Homocitrulline—an analogue and confounder related to citrulline
  • Picking the PAD lock: Chemical and biological approaches to identify PAD substrates and inhibitors.