Systems Biology of RNA Binding Proteins
After transcription in the nucleus, RNA binding proteins (RBPs) recognize cis-regulatory RNA elements within pre-mRNA sequence to form mRNA-protein (mRNP) complexes. Similarly to DNA binding proteins such as transcription factors that regulate gene expression by binding to DNA elements in the promot...
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| Další autoři: | |
| Médium: | Elektronický zdroj E-kniha |
| Jazyk: | English |
| Vydáno: |
New York, NY :
Springer New York : Imprint: Springer,
2014.
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| Vydání: | 1st ed. 2014. |
| Edice: | Advances in Experimental Medicine and Biology,
825 |
| Témata: | |
| On-line přístup: | https://doi.org/10.1007/978-1-4939-1221-6 |
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Obsah:
- Encyclopedia of RNA binding protein expression and domain annotations
- RNA localization and RNA binding proteins that control localization
- Genome-wide approaches to studying alternative polyadenylation events and the RBPs that control them
- RNA binding proteins, PRC complex and long ncRNAs
- Gene and genome regulation by piwi proteins
- Engineering Artificial RBP interactions
- Querying functional polymorphisms by high throughput binding and functional assays
- RNA binding protein networks in EMT/MET
- Therapies against diseases associated with RNA processing defects and RNA binding proteins
- Repeat-disorders and the RNA binding proteins implicated in them
- RNA binding proteins in heart development
- Identification of miRNAs and their targets in C elegans
- Splicing code
- Index.