BRAF Targets in Melanoma Biological Mechanisms, Resistance, and Drug Discovery /
This volume contains a collection of writings from the leaders in the fields of Molecular Biology and Melanoma Research which will begin to tell the ever-expanding story of the most recent findings, discoveries, and potential of BRAF-directed targets in melanoma. Recent research has shown that BRAF...
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| Andere auteurs: | |
| Formaat: | Elektronisch E-boek |
| Taal: | English |
| Gepubliceerd in: |
New York, NY :
Springer New York : Imprint: Humana,
2015.
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| Editie: | 1st ed. 2015. |
| Reeks: | Cancer Drug Discovery and Development,
82 |
| Onderwerpen: | |
| Online toegang: | https://doi.org/10.1007/978-1-4939-2143-0 |
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Inhoudsopgave:
- Melanoma: Historical Context
- Melanoma Pathogenesis
- Molecular Diagnostics and Tumor Mutational Analysis
- Clinical Utility of BRAF-targeted therapy in Melanoma
- The Ethics of Randomized Trials in Oncology
- Parallel and Serial Blockade Strategies in BRAF-Mutant Melanoma
- Targeting the cell cycle and p53 in combination with BRAF-directed therapy
- Combination BRAF-directed therapy and immunotherapy
- Moving Forward: Making BRAF-Targeted Therapy Better.