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BRAF Targets in Melanoma Biological Mechanisms, Resistance, and Drug Discovery /

This volume contains a collection of writings from the leaders in the fields of Molecular Biology and Melanoma Research which will begin to tell the ever-expanding story of the most recent findings, discoveries, and potential of BRAF-directed targets in melanoma. Recent research has shown that BRAF...

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Sparad:
Bibliografiska uppgifter
Institutionell upphovsman: SpringerLink (Online service)
Övriga upphovsmän: Sullivan, Ryan J. (Utgivare, redaktör, sammanställare, http://id.loc.gov/vocabulary/relators/edt)
Materialtyp: Elektronisk E-bok
Språk:English
Publicerad: New York, NY : Springer New York : Imprint: Humana, 2015.
Upplaga:1st ed. 2015.
Serie:Cancer Drug Discovery and Development, 82
Ämnen:
Cancer research.
Molecular biology.
Medical microbiology.
Pharmacology.
Cancer Research.
Molecular Medicine.
Medical Microbiology.
Pharmacology/Toxicology.
Länkar:https://doi.org/10.1007/978-1-4939-2143-0
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Innehållsförteckning:
  • Melanoma: Historical Context
  • Melanoma Pathogenesis
  • Molecular Diagnostics and Tumor Mutational Analysis
  • Clinical Utility of BRAF-targeted therapy in Melanoma
  • The Ethics of Randomized Trials in Oncology
  • Parallel and Serial Blockade Strategies in BRAF-Mutant Melanoma
  • Targeting the cell cycle and p53 in combination with BRAF-directed therapy
  • Combination BRAF-directed therapy and immunotherapy
  • Moving Forward: Making BRAF-Targeted Therapy Better.

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