TY - GEN TY - GEN T1 - Peptide Nucleic Acids Methods and Protocols T2 - Methods in Molecular Biology, A2 - Nielsen, Peter E. A2 - Nielsen, Peter E. LA - English PP - Totowa, NJ PB - Humana Press : Imprint: Humana YR - 2002 ED - 1st ed. 2002. UL - http://discoverylib.upm.edu.my/discovery/Record/978-1-59259-290-6 AB - Peptide nucleic acid (PNA) technology continues to grow in importance throughout molecular biology, genetic diagnostics, and molecular medicine. In Peptide Nucleic Acids: Methods and Protocols, Peter Eigil Nielsen has assembled a critically evaluated collection of PNA protocols that are either already well established around the world, such as PCR-clamping and in situ hybridization, or that display promise of significant future impact. Basic methods for PNA oligomer synthesis and analysis have also been included. Written by experts with hands-on experience in the methods they describe, these readily reproducible protocols contain detailed step-by-step instructions, tips on avoiding pitfalls and on extending the method to other situations, and introductory material explaining the theory behind the process. Up-to-date and highly practical, Peptide Nucleic Acids: Methods and Protocols provides for both novice and experienced researchers a thorough and easy introduction to the optimal use of today's PNA technology across a wide variety of fields, including molecular biology, medicinal chemistry, genetic diagnostics, and drug development. OP - 274 CN - QH345 SN - 9781592592906 KW - Biochemistry. KW - Biochemistry, general. ER -