Interferon Methods and Protocols
Although some interferons (IFNs) are widely used for their antiviral, antiproliferative, and immunoregulatory properties, there are many IFN-stimulatory genes that have unknown functions, but hold great promise in medicine and biomedical research. In Interferon Methods and Protocols, leading experts...
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| 団体著者: | |
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| その他の著者: | |
| フォーマット: | 電子媒体 eBook |
| 言語: | English |
| 出版事項: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2005.
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| 版: | 1st ed. 2005. |
| シリーズ: | Methods in Molecular Medicine,
116 |
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| オンライン･アクセス: | https://doi.org/10.1385/1592599397 |
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| 要約: | Although some interferons (IFNs) are widely used for their antiviral, antiproliferative, and immunoregulatory properties, there are many IFN-stimulatory genes that have unknown functions, but hold great promise in medicine and biomedical research. In Interferon Methods and Protocols, leading experts actively engaged in interferon research describe in detail their optimized methods to measure type I interferon efficacy as an antiproliferative or an antiviral agent. These cutting-edge techniques range from the simple to the highly complex and serve to illuminate the signaling cascades and the activation of enzymatic pathways prompted by interferon. Two chapters add an historical perspective to the field in general, discussing the successes and failures of past and present day technology, as well as the appropriate directions for consideration of future investigations. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and highly practical, Interferon Methods and Protocols offers researchers powerful tools not only to ascertain the functions of IFN-stimulatory gene products, but also to identify additional molecular pathways that will clarify our understanding of the many biological events influenced by IFNs. |
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| 物理的記述: | 240 p. 51 illus., 1 illus. in color. online resource. |
| ISBN: | 9781592599394 |
| ISSN: | 1543-1894 ; |