Peptide-Based Drug Design

Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transform...

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Yhteisötekijä: SpringerLink (Online service)
Muut tekijät: Otvos, Laszlo. (Toimittaja, http://id.loc.gov/vocabulary/relators/edt)
Aineistotyyppi: Elektroninen E-kirja
Kieli:English
Julkaistu: Totowa, NJ : Humana Press : Imprint: Humana, 2008.
Painos:1st ed. 2008.
Sarja:Methods in Molecular Biology, 494
Aiheet:
Linkit:https://doi.org/10.1007/978-1-59745-419-3
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Yhteenveto:Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo stability and imaging, and the actual production of difficult sequences. Written in the highly successful Methods in Molecular Biology™ series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, and the Notes section, which highlights tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Peptide-Based Drug Design: Methods and Protocols shows its subject to be an independent science on the rise, and provides scientists with a clear, concise guide for continuing this vital research.
Ulkoasu:XI, 303 p. online resource.
ISBN:9781597454193
ISSN:1064-3745 ;