Peptide-Based Drug Design
Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transform...
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| Natura: | Elettronico eBook |
| Lingua: | English |
| Pubblicazione: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2008.
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| Edizione: | 1st ed. 2008. |
| Serie: | Methods in Molecular Biology,
494 |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1007/978-1-59745-419-3 |
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| Riassunto: | Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo stability and imaging, and the actual production of difficult sequences. Written in the highly successful Methods in Molecular Biology™ series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, and the Notes section, which highlights tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Peptide-Based Drug Design: Methods and Protocols shows its subject to be an independent science on the rise, and provides scientists with a clear, concise guide for continuing this vital research. |
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| Descrizione fisica: | XI, 303 p. online resource. |
| ISBN: | 9781597454193 |
| ISSN: | 1064-3745 ; |