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Gamma-Glutamyl Transpeptidases Structure and Function /

 Gamma-Glutamyl Transpeptidases (γ-GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the γ-glutamyl amide bond of glutathione to liberate cysteinylglycine. The released γ-glutamyl group can be transferred to water (hydrolysis) or to amino acids or short peptid...

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Dettagli Bibliografici
Autori principali: Castellano, Immacolata. (Autore, http://id.loc.gov/vocabulary/relators/aut), Merlino, Antonello. (http://id.loc.gov/vocabulary/relators/aut)
Ente Autore: SpringerLink (Online service)
Natura: Elettronico eBook
Lingua:English
Pubblicazione: Basel : Springer Basel : Imprint: Springer, 2013.
Edizione:1st ed. 2013.
Serie:SpringerBriefs in Biochemistry and Molecular Biology,
Soggetti:
Enzymology.
Human physiology.
Biochemical engineering.
Human Physiology.
Biochemical Engineering.
Accesso online:https://doi.org/10.1007/978-3-0348-0682-4
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Sommario:
  •  1 Introduction
  • 2 Occurrence, genes and gene expression
  • 3 Structure and function of γ-GTs
  • 4 Autoprocessing and reaction mechanism of γ-GTs
  • 5 γ-GT in bioclinical
  • 6 γ-GTs: biotechnological and biomedical applications
  • 7 Conclusions
  • References.

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