Gamma-Glutamyl Transpeptidases Structure and Function /

 Gamma-Glutamyl Transpeptidases (γ-GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the γ-glutamyl amide bond of glutathione to liberate cysteinylglycine. The released γ-glutamyl group can be transferred to water (hydrolysis) or to amino acids or short peptid...

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Detalhes bibliográficos
Main Authors: Castellano, Immacolata. (Author, http://id.loc.gov/vocabulary/relators/aut), Merlino, Antonello. (http://id.loc.gov/vocabulary/relators/aut)
Autor Corporativo: SpringerLink (Online service)
Formato: Recurso Electrónico livro electrónico
Idioma:English
Publicado em: Basel : Springer Basel : Imprint: Springer, 2013.
Edição:1st ed. 2013.
Colecção:SpringerBriefs in Biochemistry and Molecular Biology,
Assuntos:
Acesso em linha:https://doi.org/10.1007/978-3-0348-0682-4
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Sumário:
  •  1 Introduction
  • 2 Occurrence, genes and gene expression
  • 3 Structure and function of γ-GTs
  • 4 Autoprocessing and reaction mechanism of γ-GTs
  • 5 γ-GT in bioclinical
  • 6 γ-GTs: biotechnological and biomedical applications
  • 7 Conclusions
  • References.