Ubiquitin Chains: Degradation and Beyond

This thesis examines the evidence for regulatory ubiquitination by focusing on A20. It provides an insightful and in-depth evaluation of the current literature by critically examining the evidence of K63-linked regulatory ubiquitination in regulating cell-signalling. It is also the first thesis to d...

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Bibliografiset tiedot
Päätekijä: De, Arnab. (Tekijä, http://id.loc.gov/vocabulary/relators/aut)
Yhteisötekijä: SpringerLink (Online service)
Aineistotyyppi: Elektroninen E-kirja
Kieli:English
Julkaistu: Cham : Springer International Publishing : Imprint: Springer, 2015.
Painos:1st ed. 2015.
Sarja:Springer Theses, Recognizing Outstanding Ph.D. Research,
Aiheet:
Linkit:https://doi.org/10.1007/978-3-319-14965-3
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Sisällysluettelo:
  • 1 Immune homeostasis: Activation and Downregulation of NF-κB
  • 2 Regulation of NF-κB signaling by regulatory ubiquitination: specific pathways and A20
  • 3 The deubiquitinase activity of A20 is dispensable for its role in NF-κB signaling
  • 4 Perspectives on regulatory ubiquitination.