Ubiquitin Chains: Degradation and Beyond
This thesis examines the evidence for regulatory ubiquitination by focusing on A20. It provides an insightful and in-depth evaluation of the current literature by critically examining the evidence of K63-linked regulatory ubiquitination in regulating cell-signalling. It is also the first thesis to d...
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| Formato: | Recurso Eletrônico livro eletrônico |
| Idioma: | English |
| Publicado em: |
Cham :
Springer International Publishing : Imprint: Springer,
2015.
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| Edição: | 1st ed. 2015. |
| coleção: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1007/978-3-319-14965-3 |
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Sumário:
- 1 Immune homeostasis: Activation and Downregulation of NF-κB
- 2 Regulation of NF-κB signaling by regulatory ubiquitination: specific pathways and A20
- 3 The deubiquitinase activity of A20 is dispensable for its role in NF-κB signaling
- 4 Perspectives on regulatory ubiquitination.