TY  - GEN
TY  - GEN
T1  - Protein-Protein Interactions as New Drug Targets
T2  - Handbook of Experimental Pharmacology,
A2  - Klussmann, Enno.
A2  - Klussmann, Enno.
A2  - Scott, John.
A2  - Scott, John.
LA  - English
PP  - Berlin, Heidelberg
PB  - Springer Berlin Heidelberg : Imprint: Springer
YR  - 2008
ED  - 1st ed. 2008.
UL  - http://discoverylib.upm.edu.my/discovery/Record/978-3-540-72843-6
AB  - Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions. This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted.
OP  - 512
CN  - RM1-950
SN  - 9783540728436
KW  - Pharmacology.
KW  - Cell biology.
KW  - Medical biochemistry.
KW  - Molecular biology.
KW  - Pharmacology/Toxicology.
KW  - Cell Biology.
KW  - Medical Biochemistry.
KW  - Molecular Medicine.
ER  -