TY - GEN TY - GEN T1 - Lead-Seeking Approaches T2 - Topics in Medicinal Chemistry, A2 - Hayward, Matthew M. A2 - Hayward, Matthew M. LA - English PP - Berlin, Heidelberg PB - Springer Berlin Heidelberg : Imprint: Springer YR - 2010 ED - 1st ed. 2010. UL - http://discoverylib.upm.edu.my/discovery/Record/978-3-642-01075-0 AB - Christopher A. Lipinski: Overview of Hit to Lead: The Medicinal Chemist’s Role from HTS Retest to Lead Optimization Hand Off Jeff W. Paslay • John E. Morin • Richard K. Harrison: High Throughput Screening in the Twenty - First Century Jack Andrew Bikker • Lakshmi S.Narasimhan: Lead Discovery Using Virtual Screening Maurizio Pellecchia: NMR Spectroscopy in Fragment Based Drug Design Kevin D. Freeman-Cook • Daniel W. Kung: Hit Triage – Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery John W. Ellingboe • Adam M. Gilbert: Lead Identification. OP - 217 CN - RS400-431 SN - 9783642010750 KW - Medicinal chemistry. KW - Neurosciences. KW - Organic chemistry. KW - Medicinal Chemistry. KW - Organic Chemistry. ER -