TY - GEN TY - GEN T1 - Effect-Directed Analysis of Complex Environmental Contamination T2 - The Handbook of Environmental Chemistry, A2 - Brack, Werner. A2 - Brack, Werner. LA - English PP - Berlin, Heidelberg PB - Springer Berlin Heidelberg : Imprint: Springer YR - 2011 ED - 1st ed. 2011. UL - http://discoverylib.upm.edu.my/discovery/Record/978-3-642-18384-3 AB - Today more than 5 million chemicals are known and roughly 100,000 of them are frequently used, with both numbers rising. Many of these chemicals are ultimately released into the environment and may cause adverse effects to ecosystems and human health. Effect-directed analysis (EDA) is a promising tool for identifying predominant toxicants in complex, mostly environmental mixtures combining effect testing, fractionation and chemical analysis. In the present book leading experts in the field provide an overview of relevant approaches and tools used in EDA. This includes diagnostic biological tools, separation techniques and advanced analytical and computer tools for toxicant identification and structure elucidation. Examples of the successful application of EDA are discussed such as the identification of mutagens in airborne particles and sediments, of endocrine disruptors in aquatic ecosystems and of major toxicants in pulp and paper mill effluents. This book is a valuable, comprehensive and interdisciplinary source of information for environmental scientists and environmental agencies dealing with the analysis, monitoring and assessment of environmental contamination. OP - 346 CN - GE1-350 SN - 9783642183843 KW - Environmental chemistry. KW - Geochemistry. KW - Analytical chemistry. KW - Environmental monitoring. KW - Ecotoxicology. KW - Pollution. KW - Environmental Chemistry. KW - Analytical Chemistry. KW - Monitoring/Environmental Analysis. KW - Pollution, general. ER -