The Islets of Langerhans
When new fellows join my lab, I give them some reading materials so that they can orient themselves in their assignment in a new eld. When fellows leave my lab, some after writing their dissertations, I prefer to give them a book as a symbolic present. I was longing for a book that contained somethi...
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| Format: | Electronic eBook |
| Language: | English |
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Dordrecht :
Springer Netherlands : Imprint: Springer,
2010.
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| Edition: | 1st ed. 2010. |
| Series: | Advances in Experimental Medicine and Biology,
654 |
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| Online Access: | https://doi.org/10.1007/978-90-481-3271-3 |
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| 001 | 978-90-481-3271-3 | ||
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| 024 | 7 | |a 10.1007/978-90-481-3271-3 |2 doi | |
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| 245 | 1 | 4 | |a The Islets of Langerhans |h [electronic resource] / |c edited by Md. Shahidul Islam. |
| 250 | |a 1st ed. 2010. | ||
| 264 | 1 | |a Dordrecht : |b Springer Netherlands : |b Imprint: Springer, |c 2010. | |
| 300 | |a XX, 798 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Advances in Experimental Medicine and Biology, |x 0065-2598 ; |v 654 | |
| 505 | 0 | |a Microscopic Anatomy of the Human Islet of Langerhans -- The Comparative Anatomy of Islets -- Approaches for Imaging Islets: Recent Advances and Future Prospects -- Islet Cell Development -- High Fat Programming of ?-Cell Failure -- Nutrient Regulation of Insulin Secretion and ?-Cell Functional Integrity -- Electrophysiology of Islet Cells -- ATP-Sensitive Potassium Channels in Health and Disease -- Role of Mitochondria in ?-cell Function and Dysfunction -- Basement Membrane in Pancreatic Islet Function -- Calcium Signaling in the Islets -- Electrical Bursting, Calcium Oscillations, and Synchronization of Pancreatic Islets -- Cyclic AMP Signaling in Pancreatic Islets -- Exocytosis in Islet ?-Cells -- The Novel Roles of Glucagon-Like Peptide-1, Angiotensin II, and Vitamin D in Islet Function -- Proteomics and Islet Research -- Wnt Signaling in Pancreatic Islets -- Molecular Pathways Underlying the Pathogenesis of Pancreatic ?-Cell Dysfunction -- Mechanisms of Pancreatic ?-Cell Apoptosis in Diabetes and Its Therapies -- ?-Cell Function in Obese-Hyperglycemic Mice [ob/ob Mice] -- Islet Structure and Function in the GK Rat -- The ?-Cell in Human Type 2 Diabetes -- Clinical Approaches to Preserve ?-Cell Function in Diabetes -- Immunology of ?-Cell Destruction -- Toll-Like Receptors and Type 1 Diabetes -- Prevention of ?-Cell Destruction in Autoimmune Diabetes: Current Approaches and Future Prospects -- In Vivo Regeneration of Insulin-Producing ?-Cells -- Customized Cell-Based Treatment Options to Combat Autoimmunity and Restore ?-Cell Function in Type 1 Diabetes Mellitus: Current Protocols and Future Perspectives -- The Programmable Cell of Monocytic Origin (PCMO): A Potential Adult Stem/Progenitor Cell Source for the Generation of Islet Cells -- Islet Isolation for Clinical Transplantation -- Human Islet Autotransplantation: The Trail Thus Far and the Highway Ahead -- Modulation of Early Inflammatory Reactions to Promote Engraftment and Function of Transplanted Pancreatic Islets in Autoimmune Diabetes -- Successes and Disappointments with Clinical Islet Transplantation -- Islet Cell Tumours. | |
| 520 | |a When new fellows join my lab, I give them some reading materials so that they can orient themselves in their assignment in a new eld. When fellows leave my lab, some after writing their dissertations, I prefer to give them a book as a symbolic present. I was longing for a book that contained something on more or less eve- thing about the islets. At the same time, I wished it contained information as recent as possible. There are a few such books in the market but they are pretty outdated. I started picking islets myself from October 1990, when I joined the Rolf Luft Center, Karolinska Institutet. Over the years my fascination for islet research remained high. Since last year, I felt a stronger urge to do more for these mysterious and hidden mini-organs that are directly or indirectly involved in the pathogenesis of all forms of diabetes that affects ?250 million people in the world. After I launched the Islet (landesbioscience. com/journals/islets) and founded the Islet Society (isletso- ety. org), there was a momentum that could be utilized to create something equally meaningful i. e. this book. The idea cracked in September 2008. Starting September 19, 2008, I contacted an estimated 90% of the authors who published anything on the islets during 2007–2008 and who could be traced from the internet. | ||
| 650 | 0 | |a Diabetes. | |
| 650 | 0 | |a Medicine. | |
| 650 | 0 | |a Cell biology. | |
| 650 | 0 | |a Cell physiology. | |
| 650 | 1 | 4 | |a Diabetes. |0 https://scigraph.springernature.com/ontologies/product-market-codes/H33045 |
| 650 | 2 | 4 | |a Biomedicine, general. |0 https://scigraph.springernature.com/ontologies/product-market-codes/B0000X |
| 650 | 2 | 4 | |a Cell Biology. |0 https://scigraph.springernature.com/ontologies/product-market-codes/L16008 |
| 650 | 2 | 4 | |a Cell Physiology. |0 https://scigraph.springernature.com/ontologies/product-market-codes/L33010 |
| 700 | 1 | |a Islam, Md. Shahidul. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9789048132737 |
| 776 | 0 | 8 | |i Printed edition: |z 9789400731943 |
| 776 | 0 | 8 | |i Printed edition: |z 9789048132706 |
| 830 | 0 | |a Advances in Experimental Medicine and Biology, |x 0065-2598 ; |v 654 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-90-481-3271-3 |
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