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Phosphoinositides I: Enzymes of Synthesis and Degradation

Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegene...

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Bibliografiske detaljer
Institution som forfatter: SpringerLink (Online service)
Andre forfattere: Balla, Tamas. (Editor, http://id.loc.gov/vocabulary/relators/edt), Wymann, Matthias. (Editor, http://id.loc.gov/vocabulary/relators/edt), York, John D. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Format: Electronisk eBog
Sprog:English
Udgivet: Dordrecht : Springer Netherlands : Imprint: Springer, 2012.
Udgivelse:1st ed. 2012.
Serier:Subcellular Biochemistry, 58
Fag:
Medicine.
Neurosciences.
Human genetics.
Molecular biology.
Medical genetics.
Neurochemistry.
Biomedicine, general.
Human Genetics.
Molecular Medicine.
Gene Function.
Online adgang:https://doi.org/10.1007/978-94-007-3012-0
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Indholdsfortegnelse:
  • 1. The Phosphatidylinositol 4-kinases: Don’t Call it a Comeback
  • 2. PIP kinases from the cell membrane to the nucleus
  • 3. The Phospholipase C Isozymes and Their Regulation.- 4. Phosphoinositide 3-Kinases – A Historical Perspective
  • 5. PI 3-kinases – drug targets in inflammation and cancer
  • 6. Phosphoinositide 3-kinases in health and disease
  • 7. Phosphoinositide phosphatases: just as important as the kinases
  • 8. The PTEN and myobubularin phosphoinositide 3-phosphatases: linking lipid signalling to human disease.

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