Histopathological assessment of acetaminophen-induced liver injury and regeneration response following edible bird’s nest administration in ICR and BALB/C mice model
Acetaminophen (APAP) overdose is known to induce liver injury in mice models and humans. Excessive accumulation of reactive metabolite, N-acetyl-p-benzoquinone-imine (NAPQI) increases oxidative stress in tissues, leading to centrilobular necrosis after exceeding the glutathione (GSH) threshold. Alth...
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| Autor principal: | |
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| Formato: | Tese |
| Idioma: | English |
| Publicado em: |
2021
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| Acesso em linha: | http://ethesis.upm.edu.my/id/eprint/16254/1/FPV%202021%2017%20UPMT.pdf |
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