Transgene Silencing Following Lentiviral Gene Delivery into Hematopoietic Stem Cells
Gene therapy shows increasing promise for the treatment of hematopoietic inherited diseases such as β-thalassemia. One of the main barriers for a successful gene therapy is the short-lived duration of gene expression in vivo, a phenomenon known as transgene silencing. Unlike other viral methods, len...
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| Format: | Thèse |
| Langue: | English English |
| Publié: |
2011
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| Accès en ligne: | http://ethesis.upm.edu.my/id/eprint/6100/1/FPSK%28p%29%202011%207.pdf http://ethesis.upm.edu.my/id/eprint/6100/7/FPSK%28p%29%202011%207_n.pdf |
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