Process development with bifunctional chiral epoxides to acess single enantiomers of pharmaceutical intermediates

Two selected case studies on process development will be discussed: one is on the enantiocontrolled synthesis of (S)-3-hydroxytetradecanoic acid (2), an intermediate of ONO-4007 (3) possessing anti tumor activity, which employs terminally differentiated double homologation on (S)-epichlorohydrin (EC...

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Bibliographic Details
Main Authors: Ikunaka, Masaya, Sugai, Takeshi
Format: Proceedings Paper
Language:English
Published: Malaysian Palm oil Board 2015
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Online Access:http://agris.upm.edu.my:8080/dspace/handle/0/8328
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