Predicting deleterious non-synonymous single nucleotide polymorphisms nsSNPs of HRAS gene and in-silico evaluation of their structural and functional consequences towards diagnosis and prognosis of cancer
The Harvey rat sarcoma (HRAS) proto-oncogene belongs to the RAS family and is one of the pathogenic genes that cause cancer. Deleterious nsSNPs might have adverse consequences at the protein level. This study aimed to investigate deleterious nsSNPs in the HRAS gene in predicting structural alteratio...
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| Médium: | Článek |
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MDPI
2022
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