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Antifungal properties of Allium sativum extracts on Candida species

Candida albicans, Candida tropicalis and Candida krusei frequently cause many infections in immunodeficient humans. The infection invariably becomes invasive and disseminate to other body sites. Tests of antifungal effect of Azadirachta indica (Neem), Peperomia pellucida (“ketumpang air”) and Allium...

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Principais autores: Low, Chen Fei, Yong, Phelim Voon Chen, Ahmad, Zuraini, Othman, Fauziah, Chong, Pei Pei
Formato: Atigo
Idioma:English
Publicado em: Total Health Concept Sdn.bhd 2008
Acesso em linha:http://psasir.upm.edu.my/id/eprint/13143/1/Antifungal%20properties%20of%20Allium%20sativum%20extracts%20on%20Candida%20species.pdf
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id oai:psasir.upm.edu.my:13143
record_format eprints
spelling oai:psasir.upm.edu.my:13143 http://psasir.upm.edu.my/id/eprint/13143/ Antifungal properties of Allium sativum extracts on Candida species Low, Chen Fei Yong, Phelim Voon Chen Ahmad, Zuraini Othman, Fauziah Chong, Pei Pei Candida albicans, Candida tropicalis and Candida krusei frequently cause many infections in immunodeficient humans. The infection invariably becomes invasive and disseminate to other body sites. Tests of antifungal effect of Azadirachta indica (Neem), Peperomia pellucida (“ketumpang air”) and Allium sativum (Garlic) extracts on the three Candida species through paper disc diffusion method showed that all the three Candida species were resistant to A. indica and P. pellucida, but susceptible to A. sativum extract. Subsequently, the effect of different concentrations of garlic extract on the growth of C. albicans was evaluated to determine the IC50 and LD50. The effect of garlic extract suggests that sublethal doses can reduce the colonization of Candida species in the oral cavity of humans by suppressing the virulent hyphal growth form. Total Health Concept Sdn.bhd 2008-06 Article NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13143/1/Antifungal%20properties%20of%20Allium%20sativum%20extracts%20on%20Candida%20species.pdf Low, Chen Fei and Yong, Phelim Voon Chen and Ahmad, Zuraini and Othman, Fauziah and Chong, Pei Pei (2008) Antifungal properties of Allium sativum extracts on Candida species. Journal of Tropical Medicinal Plants, 9 (1). pp. 43-48. ISSN 1511-8525
institution UPM IR
collection UPM IR
language English
description Candida albicans, Candida tropicalis and Candida krusei frequently cause many infections in immunodeficient humans. The infection invariably becomes invasive and disseminate to other body sites. Tests of antifungal effect of Azadirachta indica (Neem), Peperomia pellucida (“ketumpang air”) and Allium sativum (Garlic) extracts on the three Candida species through paper disc diffusion method showed that all the three Candida species were resistant to A. indica and P. pellucida, but susceptible to A. sativum extract. Subsequently, the effect of different concentrations of garlic extract on the growth of C. albicans was evaluated to determine the IC50 and LD50. The effect of garlic extract suggests that sublethal doses can reduce the colonization of Candida species in the oral cavity of humans by suppressing the virulent hyphal growth form.
format Article
author Low, Chen Fei
Yong, Phelim Voon Chen
Ahmad, Zuraini
Othman, Fauziah
Chong, Pei Pei
spellingShingle Low, Chen Fei
Yong, Phelim Voon Chen
Ahmad, Zuraini
Othman, Fauziah
Chong, Pei Pei
Antifungal properties of Allium sativum extracts on Candida species
author_facet Low, Chen Fei
Yong, Phelim Voon Chen
Ahmad, Zuraini
Othman, Fauziah
Chong, Pei Pei
author_sort Low, Chen Fei
title Antifungal properties of Allium sativum extracts on Candida species
title_short Antifungal properties of Allium sativum extracts on Candida species
title_full Antifungal properties of Allium sativum extracts on Candida species
title_fullStr Antifungal properties of Allium sativum extracts on Candida species
title_full_unstemmed Antifungal properties of Allium sativum extracts on Candida species
title_sort antifungal properties of allium sativum extracts on candida species
publisher Total Health Concept Sdn.bhd
publishDate 2008
url http://psasir.upm.edu.my/id/eprint/13143/1/Antifungal%20properties%20of%20Allium%20sativum%20extracts%20on%20Candida%20species.pdf
_version_ 1819293680742170624
score 13.4562235

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