TY  - JOUR
T1  - Antileukemic activity and chemical constituents of some Zingiberaceae species
A1  - Md.Sukari, Mohd. Aspollah
LA  - English
PB  - Chemic Publishing Company
YR  - 2010
UL  - http://discoverylib.upm.edu.my/discovery/Record/oai:psasir.upm.edu.my:13155
AB  - Crude extracts of various solvents from six species (genus Alpinia, Zingiber, Kaempferia) of Zingiberaceae family have been chosen for the in vitro cytotoxic activity screening against the inhibition of HL-60 cell line (Human promyelocytic leukemia). Eight extracts (44 %) were found to have cytotoxic activity with IC50 values less than 30 μg/mL, with Alpinia galanga showing the most prominent antileukemic activity. Further isolation work on Kaempferia galanga has yielded ethyl p-methoxy-trans-cinnamate (1), p-methoxy-trans-cinnamic acid (2) besides b-sitosterol.
ER  -