Enhanced interferon-α2b production in periplasmic space of Escherichia coli through medium optimization using response surface method

The influence of different carbon and nitrogen sources on growth of recombinant Escherichia coli and human interferon-α2b (IFN-α2b) production in periplasmic space was studied in shake flask culture. A statistical method based on Plackett-Burman design was used to screen the main medium components t...

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Auteurs principaux: Tan, Joo Shun, Ramanan, Ramakrishnan Nagasundara, Azaman, Siti Nor Ani, Ling, Tau Chuan, Mustafa, Shuhaimi, Ariff, Arbakariya
Format: Article
Langue:English
Publié: Bentham Open 2009
Accès en ligne:http://psasir.upm.edu.my/id/eprint/14509/1/Enhanced%20interferon-%CE%B12b%20production%20in%20periplasmic%20space%20of%20Escherichia%20coli%20through%20medium%20optimization%20using%20response%20surface%20method.pdf
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