Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity
In this study, antibacterial characteristic of silver/poly (lactic acid) nanocomposite (Ag/PLA-NC) films was investigated, while silver nanoparticles (Ag-NPs) were synthesized into biodegradable PLA via chemical reduction method in diphase solvent. Silver nitrate and sodium borohydride were respecti...
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2010
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oai:psasir.upm.edu.my:16710 http://psasir.upm.edu.my/id/eprint/16710/ Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity Shameli, Kamyar Ahmad, Mansor Wan Yunus, Wan Md. Zin Ibrahim, Nor Azowa Abdul Rahman, Russly Jokar, Maryam Darroudi, Majid In this study, antibacterial characteristic of silver/poly (lactic acid) nanocomposite (Ag/PLA-NC) films was investigated, while silver nanoparticles (Ag-NPs) were synthesized into biodegradable PLA via chemical reduction method in diphase solvent. Silver nitrate and sodium borohydride were respectively used as a silver precursor and reducing agent in the PLA, which acted as a polymeric matrix and stabilizer. Meanwhile, the properties of Ag/PLA-NCs were studied as a function of the Ag-NP weight percentages (8, 16, and 32 wt% respectively), in relation to the use of PLA. The morphology of the Ag/PLA-NC films and the distribution of the Ag-NPs were also characterized. The silver ions released from the Ag/PLA-NC films and their antibacterial activities were scrutinized. The antibacterial activities of the Ag/PLA-NC films were examined against Gram-negative bacteria (Escherichia coli and Vibrio parahaemolyticus) and Gram-positive bacteria (Staphylococcus aureus) by diffusion method using Muller–Hinton agar. The results indicated that Ag/PLA-NC films possessed a strong antibacterial activity with the increase in the percentage of Ag-NPs in the PLA. Thus, Ag/PLA-NC films can be used as an antibacterial scaffold for tissue engineering and medical application. Dove Medical Press Ltd. 2010-08 Article PeerReviewed Shameli, Kamyar and Ahmad, Mansor and Wan Yunus, Wan Md. Zin and Ibrahim, Nor Azowa and Abdul Rahman, Russly and Jokar, Maryam and Darroudi, Majid (2010) Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity. International Journal of Nanomedicine, 5. pp. 573-579. ISSN 1176-9114 Nanocomposites (Materials) Nanoparticles Antibacterial agents 10.2147/IJN.S12007 English |
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Nanocomposites (Materials) Nanoparticles Antibacterial agents |
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Nanocomposites (Materials) Nanoparticles Antibacterial agents Shameli, Kamyar Ahmad, Mansor Wan Yunus, Wan Md. Zin Ibrahim, Nor Azowa Abdul Rahman, Russly Jokar, Maryam Darroudi, Majid Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| description |
In this study, antibacterial characteristic of silver/poly (lactic acid) nanocomposite (Ag/PLA-NC) films was investigated, while silver nanoparticles (Ag-NPs) were synthesized into biodegradable PLA via chemical reduction method in diphase solvent. Silver nitrate and sodium borohydride were respectively used as a silver precursor and reducing agent in the PLA, which acted as a polymeric matrix and stabilizer. Meanwhile, the properties of
Ag/PLA-NCs were studied as a function of the Ag-NP weight percentages (8, 16, and 32 wt% respectively), in relation to the use of PLA. The morphology of the Ag/PLA-NC films and
the distribution of the Ag-NPs were also characterized. The silver ions released from the Ag/PLA-NC films and their antibacterial activities were scrutinized. The antibacterial activities of the Ag/PLA-NC films were examined against Gram-negative bacteria (Escherichia
coli and Vibrio parahaemolyticus) and Gram-positive bacteria (Staphylococcus aureus) by diffusion method using Muller–Hinton agar. The results indicated that Ag/PLA-NC films possessed a strong antibacterial activity with the increase in the percentage of Ag-NPs in the PLA. Thus, Ag/PLA-NC films can be used as an antibacterial scaffold for tissue engineering and medical application. |
| format |
Article |
| author |
Shameli, Kamyar Ahmad, Mansor Wan Yunus, Wan Md. Zin Ibrahim, Nor Azowa Abdul Rahman, Russly Jokar, Maryam Darroudi, Majid |
| author_facet |
Shameli, Kamyar Ahmad, Mansor Wan Yunus, Wan Md. Zin Ibrahim, Nor Azowa Abdul Rahman, Russly Jokar, Maryam Darroudi, Majid |
| author_sort |
Shameli, Kamyar |
| title |
Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title_short |
Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title_full |
Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title_fullStr |
Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title_full_unstemmed |
Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title_sort |
silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| publisher |
Dove Medical Press Ltd. |
| publishDate |
2010 |
| _version_ |
1819294058150887424 |
| score |
13.4562235 |