Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.

The copy number variation in beta-defensin genes on human chromosome 8 has been proposed to underlie susceptibility to inflammatory disorders, but presents considerable challenges for accurate typing on the scale required for adequately powered case-control studies. In this work, we have used accura...

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Huvudupphovsmän: Aldhous, Marian C., Abu Bakar @ Jamaludin, Suhaili, Prescott, Natalie J., Palla, Raquel, Soo, Kimberley, Mansfield, John C., Mathew, Christopher G., Satsangi, Jack, Armour, A. L.
Materialtyp: Artikel
Språk:English
English
Publicerad: Oxford University Press 2010
Länkar:http://psasir.upm.edu.my/id/eprint/24407/1/Measurement%20methods%20and%20accuracy%20in%20copy%20number%20variation.pdf
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