Depression and quality of life among patients with hematological cancer in a Malaysian hospital

Objective: To determine the prevalence of major depressive disorder (MDD) in hematological cancer patients and to investigate MDD with quality of life. Methods: The research, which uses a cross sectional design, has been carried out at Ampang Hospital, Kuala Lumpur. The hospital is a tertiary referr...

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Main Authors: Das, Priscilla, Awang, Hamidin, Md. Zain, Azhar, Naing, Khin Ohnmar@Noor Jan, Md Said, Salmiah, Khalid, Bahariah
Format: Article
Language:English
English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2011
Online Access:http://psasir.upm.edu.my/id/eprint/24544/1/Depression%20and%20Quality%20of%20Life%20among%20Patients%20with%20Hematological%20Cancer.pdf
http://psasir.upm.edu.my/id/eprint/24544/7/Depression%20and%20quality%20of%20life%20among%20patients%20with%20hematological%20cancer%20in%20a%20Malaysian%20hospital.pdf
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spelling oai:psasir.upm.edu.my:24544 http://psasir.upm.edu.my/id/eprint/24544/ Depression and quality of life among patients with hematological cancer in a Malaysian hospital Das, Priscilla Awang, Hamidin Md. Zain, Azhar Naing, Khin Ohnmar@Noor Jan Md Said, Salmiah Khalid, Bahariah Objective: To determine the prevalence of major depressive disorder (MDD) in hematological cancer patients and to investigate MDD with quality of life. Methods: The research, which uses a cross sectional design, has been carried out at Ampang Hospital, Kuala Lumpur. The hospital is a tertiary referral center for cancer cases that include non-Hodgkin lymphoma, acute myelogenous leukemia, acute lymphoblastic leukemia, Hodgkin lymphoma and other hematological cancers. In total, 105 patients with hematological malignancies were included in the study. This study employed the MINI International Neuropsychiatric Interview for diagnosis of MDD, the Patient Health Questionnaire (PHQ-9) for symptom severity of depression and the European Organisation for Research and Treatment of Cancer Quality Of Life questionnaire (EORTC QLQ-C30) to assess the quality of life of the respondents. Result: The response rate was 83.3%. The prevalence of MDD was 24.8% (n=26) with the majority of cases classified as moderately severe depression (38.5%). About 92.3% (n=24) of depressed hematological cancer patients were diagnosed with a current episode of MDD. The depressed patients also had significantly reduced quality of life in physical, role, emotional, cognitive and social domains (p<0.05). They also had significantly more symptoms of fatigue, nausea and vomiting, dyspnea, insomnia, appetite loss, constipation and diarrhea in addition to having financial difficulties and poor global health statuses (p<0.05). Conclusion: The prevalence of depression among the hematological cancer patients was high and the depressed patients had reduced qualities of life. Special attention in psychotherapy would help to improve both depression level and the quality of life in these patients. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2011-01 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24544/1/Depression%20and%20Quality%20of%20Life%20among%20Patients%20with%20Hematological%20Cancer.pdf application/pdf en http://psasir.upm.edu.my/id/eprint/24544/7/Depression%20and%20quality%20of%20life%20among%20patients%20with%20hematological%20cancer%20in%20a%20Malaysian%20hospital.pdf Das, Priscilla and Awang, Hamidin and Md. Zain, Azhar and Naing, Khin Ohnmar@Noor Jan and Md Said, Salmiah and Khalid, Bahariah (2011) Depression and quality of life among patients with hematological cancer in a Malaysian hospital. Malaysian Journal of Medicine and Health Sciences, 7 (1). pp. 65-74. ISSN 1675-8544 http://www.medic.upm.edu.my/dokumen/FKUSK1_MJMHS_2011V07N1_OP10.pdf
institution UPM IR
collection UPM IR
language English
English
description Objective: To determine the prevalence of major depressive disorder (MDD) in hematological cancer patients and to investigate MDD with quality of life. Methods: The research, which uses a cross sectional design, has been carried out at Ampang Hospital, Kuala Lumpur. The hospital is a tertiary referral center for cancer cases that include non-Hodgkin lymphoma, acute myelogenous leukemia, acute lymphoblastic leukemia, Hodgkin lymphoma and other hematological cancers. In total, 105 patients with hematological malignancies were included in the study. This study employed the MINI International Neuropsychiatric Interview for diagnosis of MDD, the Patient Health Questionnaire (PHQ-9) for symptom severity of depression and the European Organisation for Research and Treatment of Cancer Quality Of Life questionnaire (EORTC QLQ-C30) to assess the quality of life of the respondents. Result: The response rate was 83.3%. The prevalence of MDD was 24.8% (n=26) with the majority of cases classified as moderately severe depression (38.5%). About 92.3% (n=24) of depressed hematological cancer patients were diagnosed with a current episode of MDD. The depressed patients also had significantly reduced quality of life in physical, role, emotional, cognitive and social domains (p<0.05). They also had significantly more symptoms of fatigue, nausea and vomiting, dyspnea, insomnia, appetite loss, constipation and diarrhea in addition to having financial difficulties and poor global health statuses (p<0.05). Conclusion: The prevalence of depression among the hematological cancer patients was high and the depressed patients had reduced qualities of life. Special attention in psychotherapy would help to improve both depression level and the quality of life in these patients.
format Article
author Das, Priscilla
Awang, Hamidin
Md. Zain, Azhar
Naing, Khin Ohnmar@Noor Jan
Md Said, Salmiah
Khalid, Bahariah
spellingShingle Das, Priscilla
Awang, Hamidin
Md. Zain, Azhar
Naing, Khin Ohnmar@Noor Jan
Md Said, Salmiah
Khalid, Bahariah
Depression and quality of life among patients with hematological cancer in a Malaysian hospital
author_facet Das, Priscilla
Awang, Hamidin
Md. Zain, Azhar
Naing, Khin Ohnmar@Noor Jan
Md Said, Salmiah
Khalid, Bahariah
author_sort Das, Priscilla
title Depression and quality of life among patients with hematological cancer in a Malaysian hospital
title_short Depression and quality of life among patients with hematological cancer in a Malaysian hospital
title_full Depression and quality of life among patients with hematological cancer in a Malaysian hospital
title_fullStr Depression and quality of life among patients with hematological cancer in a Malaysian hospital
title_full_unstemmed Depression and quality of life among patients with hematological cancer in a Malaysian hospital
title_sort depression and quality of life among patients with hematological cancer in a malaysian hospital
publisher Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
publishDate 2011
url http://psasir.upm.edu.my/id/eprint/24544/1/Depression%20and%20Quality%20of%20Life%20among%20Patients%20with%20Hematological%20Cancer.pdf
http://psasir.upm.edu.my/id/eprint/24544/7/Depression%20and%20quality%20of%20life%20among%20patients%20with%20hematological%20cancer%20in%20a%20Malaysian%20hospital.pdf
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