Upregulation of genes related to bone formation by y-amino butyric acid and y-oryzanol in pre-germinated brown rice is via the activation of GABAB-receptors and reduction in serum IL-6 in rats

Background: Osteoporosis and other bone degenerative diseases are among the most challenging non-communicable diseases to treat. Previous works relate bone loss due to osteoporosis with oxidative stress generated by free radicals and inflammatory cytokines. Alternative therapy to hormone replacemen...

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Bibliographic Details
Main Authors: Muhammad Sani, Ismaila, Ismail, Maznah, Mahmud, Rozi, Abu Bakar @ Zakaria, Md Zuki, Imam, Mustapha Umar
Format: Article
Language:English
Published: Dove Medical Press 2013
Online Access:http://psasir.upm.edu.my/id/eprint/29627/1/29627.pdf