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Inhibition of hypoxia-inducible factor activity with Carica papaya extracts

An extract of Carica papaya leaves is used as an inhibitor of HIF to effectively block hypoxia-inducible factor (HIF) function and methods of use thereof. More specifically it relates to the use of Carica papaya plant extract to eliminate unwanted cells by inhibiting HIF in the prevention and treatm...

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Main Authors: Shafee, Norazizah, Yusoff, Khatijah, Stanbridge, Eric J.
Format: Patent
Izdano: 2013
Oznake: Označite
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id oai:psasir.upm.edu.my:33664
record_format eprints
spelling oai:psasir.upm.edu.my:33664 http://psasir.upm.edu.my/id/eprint/33664/ Inhibition of hypoxia-inducible factor activity with Carica papaya extracts Shafee, Norazizah Yusoff, Khatijah Stanbridge, Eric J. An extract of Carica papaya leaves is used as an inhibitor of HIF to effectively block hypoxia-inducible factor (HIF) function and methods of use thereof. More specifically it relates to the use of Carica papaya plant extract to eliminate unwanted cells by inhibiting HIF in the prevention and treatment of hypoxia-related conditions and diseases such as inflammatory diseases, vascular diseases, cancer and infectious diseases. In a particular embodiment, a solid hypoxic tumor in a patient is treated by administering to the patient a therapeutically acceptable amount of an extract of Carica papaya leaves, preferably an alcohol extract such as a methanol extract, whereby to inhibit hypoxia-inducible factors in the tumor. 2013-06-28 Patent NonPeerReviewed Norazizah Shafee (2013) Inhibition of hypoxia-inducible factor activity with Carica papaya extracts. PI 2013701142.
institution UPM IR
collection UPM IR
description An extract of Carica papaya leaves is used as an inhibitor of HIF to effectively block hypoxia-inducible factor (HIF) function and methods of use thereof. More specifically it relates to the use of Carica papaya plant extract to eliminate unwanted cells by inhibiting HIF in the prevention and treatment of hypoxia-related conditions and diseases such as inflammatory diseases, vascular diseases, cancer and infectious diseases. In a particular embodiment, a solid hypoxic tumor in a patient is treated by administering to the patient a therapeutically acceptable amount of an extract of Carica papaya leaves, preferably an alcohol extract such as a methanol extract, whereby to inhibit hypoxia-inducible factors in the tumor.
format Patent
author Shafee, Norazizah
Yusoff, Khatijah
Stanbridge, Eric J.
spellingShingle Shafee, Norazizah
Yusoff, Khatijah
Stanbridge, Eric J.
Inhibition of hypoxia-inducible factor activity with Carica papaya extracts
author_facet Shafee, Norazizah
Yusoff, Khatijah
Stanbridge, Eric J.
author_sort Shafee, Norazizah
title Inhibition of hypoxia-inducible factor activity with Carica papaya extracts
title_short Inhibition of hypoxia-inducible factor activity with Carica papaya extracts
title_full Inhibition of hypoxia-inducible factor activity with Carica papaya extracts
title_fullStr Inhibition of hypoxia-inducible factor activity with Carica papaya extracts
title_full_unstemmed Inhibition of hypoxia-inducible factor activity with Carica papaya extracts
title_sort inhibition of hypoxia-inducible factor activity with carica papaya extracts
publishDate 2013
_version_ 1819295616903151616
score 13.4562235

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