Free radical scavenging activity of Syzygium polyanthum leaves
There is a growing interest in the usage of antioxidants in attempt to prevent oxidative damage caused by free radicals in the human body. This study was undertaken to determine the free radical scavenging activity of methanolic extract of Syzygium polyanthum (SP) leaves against the stable 2,2-Azino...
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2012
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oai:psasir.upm.edu.my:50247 http://psasir.upm.edu.my/id/eprint/50247/ Free radical scavenging activity of Syzygium polyanthum leaves Yassir, M. A. Abdul Kadir, Arifah Ismail, Amin Othman, Fauziah There is a growing interest in the usage of antioxidants in attempt to prevent oxidative damage caused by free radicals in the human body. This study was undertaken to determine the free radical scavenging activity of methanolic extract of Syzygium polyanthum (SP) leaves against the stable 2,2-Azino-bis-3-ethylbenzothiazoline-6-sulfonic Acid (ABTS) radical by using an ELISA reader technique. The results showed that SP directly reacted and quenched ABTS free radicals in the system. The IC50 value of SP was significantly (P <0.05) more effective than that of ascorbic acid, and quenched significantly (P <0.05) more ABTS radicals at low concentrations (5 and 10 μg/mL) than that of ascorbic acid. Moreover, the total antioxidant capacity (TAC) of SP was also significantly (P <0.05) higher than that of ascorbic acid under same experimental condition. In conclusion, the results of ABTS assay reveal potent antioxidant and free radical scavenging activity of SP higher than that of standard ascorbic acid which may serve as a new natural antioxidant. 2012 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/50247/1/2-19.pdf Yassir, M. A. and Abdul Kadir, Arifah and Ismail, Amin and Othman, Fauziah (2012) Free radical scavenging activity of Syzygium polyanthum leaves. In: International Conference on One Health and 24th VAM Congress 2012, 21-23 Sept. 2012, Marriott Putrajaya. (pp. 399-401). |
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English |
| description |
There is a growing interest in the usage of antioxidants in attempt to prevent oxidative damage caused by free radicals in the human body. This study was undertaken to determine the free radical scavenging activity of methanolic extract of Syzygium polyanthum (SP) leaves against the stable 2,2-Azino-bis-3-ethylbenzothiazoline-6-sulfonic Acid (ABTS) radical by using an ELISA reader technique. The results showed that SP directly reacted and quenched ABTS free radicals in the system. The IC50 value of SP was significantly (P <0.05) more effective than that of ascorbic acid, and quenched significantly (P <0.05) more ABTS radicals at low concentrations (5 and 10 μg/mL) than that of ascorbic acid. Moreover, the total antioxidant capacity (TAC) of SP was also significantly (P <0.05) higher than that of ascorbic acid under same experimental condition. In conclusion, the results of ABTS assay reveal potent antioxidant and free radical scavenging activity of SP higher than that of standard ascorbic acid which may serve as a new natural antioxidant. |
| format |
Conference or Workshop Item |
| author |
Yassir, M. A. Abdul Kadir, Arifah Ismail, Amin Othman, Fauziah |
| spellingShingle |
Yassir, M. A. Abdul Kadir, Arifah Ismail, Amin Othman, Fauziah Free radical scavenging activity of Syzygium polyanthum leaves |
| author_facet |
Yassir, M. A. Abdul Kadir, Arifah Ismail, Amin Othman, Fauziah |
| author_sort |
Yassir, M. A. |
| title |
Free radical scavenging activity of Syzygium polyanthum leaves |
| title_short |
Free radical scavenging activity of Syzygium polyanthum leaves |
| title_full |
Free radical scavenging activity of Syzygium polyanthum leaves |
| title_fullStr |
Free radical scavenging activity of Syzygium polyanthum leaves |
| title_full_unstemmed |
Free radical scavenging activity of Syzygium polyanthum leaves |
| title_sort |
free radical scavenging activity of syzygium polyanthum leaves |
| publishDate |
2012 |
| url |
http://psasir.upm.edu.my/id/eprint/50247/1/2-19.pdf |
| _version_ |
1819297032815247360 |
| score |
13.4562235 |