SRJ09, a promising anticancer drug lead: elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy

SRJ09 (3,19-(2-bromobenzylidene)andrographolide), a semisynthetic andrographolide (AGP) derivative, was shown to induce G1 cell cycle arrest and eventually apoptosis in breast and colon cancer cell lines. The present investigation was carried out to elucidate the mechanisms cell cycle arrest and apo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wong, Charng Choon, Lim, Siang Hui, Sagineedu, Sreenivasa Rao, Lajis, Nordin, Stanslas, Johnson
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Elsevier 2016
Pynciau:
Mynediad Ar-lein:http://psasir.upm.edu.my/id/eprint/53871/1/SRJ09%2C%20a%20promising%20anticancer%20drug%20lead.pdf
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