SRJ09, a promising anticancer drug lead: elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy
SRJ09 (3,19-(2-bromobenzylidene)andrographolide), a semisynthetic andrographolide (AGP) derivative, was shown to induce G1 cell cycle arrest and eventually apoptosis in breast and colon cancer cell lines. The present investigation was carried out to elucidate the mechanisms cell cycle arrest and apo...
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| Main Authors: | , , , , |
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| Format: | Article |
| Sprog: | English |
| Udgivet: |
Elsevier
2016
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| Fag: | |
| Online adgang: | http://psasir.upm.edu.my/id/eprint/53871/1/SRJ09%2C%20a%20promising%20anticancer%20drug%20lead.pdf |
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