Development of tat - conjugated dendrimer for transdermal DNA vaccine delivery

PURPOSE: In order to enhance cellular uptake and to facilitate transdermal delivery of DNA vaccine, polyamidoamine (PAMAM) dendrimers conjugated with HIV transactivator of transcription (TAT) was developed. METHODS: First, the plasmid DNA (pIRES-H5/GFP) nanoparticle was formulated using PAMAM d...

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Main Authors: Bahadoran, Azadeh, Moeini, Hassan, Bejo, Mohd Hair, Hussein, Mohd Zobir, Omar, Abdul Rahman
Format: Article
Sprog:English
Udgivet: Canadian Society for Pharmaceutical Sciences 2016
Online adgang:http://psasir.upm.edu.my/id/eprint/55505/1/Development%20of%20Tat-Conjugated%20Dendrimer%20for%20Transdermal%20DNA%20Vaccine%20Delivery..pdf
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