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Mercury contamination in facial skin lightening creams and its health risks to user

This study aims to determine concentrations of mercury in facial skin lightening cream according to different price categories (category I: <RM29.99, category II: RM30.00-RM59.99, category III: RM60.00-RM99.99 and category IV: ≥RM100.00) and their potential health risks to users. Prices of skin l...

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Main Authors: Ho, Yu Bin, Abdullah, Nor Hidayu, Hamsan, Hazwanee, Tan, Eugenie Sin Sing
Format: Article
Jezik:English
Izdano: Academic Press 2017
Online dostop:http://psasir.upm.edu.my/id/eprint/62393/1/Mercury%20contamination%20in%20facial%20skin%20lightening%20creams%20and%20its%20health%20risks%20to%20user.pdf
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spelling oai:psasir.upm.edu.my:62393 http://psasir.upm.edu.my/id/eprint/62393/ Mercury contamination in facial skin lightening creams and its health risks to user Ho, Yu Bin Abdullah, Nor Hidayu Hamsan, Hazwanee Tan, Eugenie Sin Sing This study aims to determine concentrations of mercury in facial skin lightening cream according to different price categories (category I: <RM29.99, category II: RM30.00-RM59.99, category III: RM60.00-RM99.99 and category IV: ≥RM100.00) and their potential health risks to users. Prices of skin lightening creams were determined during a preliminary market survey. Thereafter, twenty samples were purchased from various locations such as cosmetic stalls, beauty shops, pharmacies and street vendors based on their stratified price categories. Samples were extracted using microwave digester and analyzed using cold vapor atomic absorption spectrometry (CV-AAS). Non-carcinogenic chronic health risks for application of facial skin lightening cream were calculated using Dermal Absorption Dose (DAD) and Hazard Quotient (HQ). Concentrations of mercury in samples were less than the United States Food and Drug Administration (USFDA) permitted trace levels (<1 ppm) except for one sample from category III which was manufactured in China. Concentrations of mercury in facial skin lightening creams ranged from not detected to 1.13 mg kg−1. There was no significant association between concentrations of mercury with price categories (p = 0.12). There was no significant non-carcinogenic health risk due to daily application of the facial skin lightening creams based on assumption of 30 years exposure period (HQ < 1). Academic Press 2017-08 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/62393/1/Mercury%20contamination%20in%20facial%20skin%20lightening%20creams%20and%20its%20health%20risks%20to%20user.pdf Ho, Yu Bin and Abdullah, Nor Hidayu and Hamsan, Hazwanee and Tan, Eugenie Sin Sing (2017) Mercury contamination in facial skin lightening creams and its health risks to user. Regulatory Toxicology and Pharmacology, 88. pp. 72-76. ISSN 0273-2300; ESSN: 1096-0295 https://www.sciencedirect.com/science/article/pii/S0273230017301472?via%3Dihub 10.1016/j.yrtph.2017.05.018
institution UPM IR
collection UPM IR
language English
description This study aims to determine concentrations of mercury in facial skin lightening cream according to different price categories (category I: <RM29.99, category II: RM30.00-RM59.99, category III: RM60.00-RM99.99 and category IV: ≥RM100.00) and their potential health risks to users. Prices of skin lightening creams were determined during a preliminary market survey. Thereafter, twenty samples were purchased from various locations such as cosmetic stalls, beauty shops, pharmacies and street vendors based on their stratified price categories. Samples were extracted using microwave digester and analyzed using cold vapor atomic absorption spectrometry (CV-AAS). Non-carcinogenic chronic health risks for application of facial skin lightening cream were calculated using Dermal Absorption Dose (DAD) and Hazard Quotient (HQ). Concentrations of mercury in samples were less than the United States Food and Drug Administration (USFDA) permitted trace levels (<1 ppm) except for one sample from category III which was manufactured in China. Concentrations of mercury in facial skin lightening creams ranged from not detected to 1.13 mg kg−1. There was no significant association between concentrations of mercury with price categories (p = 0.12). There was no significant non-carcinogenic health risk due to daily application of the facial skin lightening creams based on assumption of 30 years exposure period (HQ < 1).
format Article
author Ho, Yu Bin
Abdullah, Nor Hidayu
Hamsan, Hazwanee
Tan, Eugenie Sin Sing
spellingShingle Ho, Yu Bin
Abdullah, Nor Hidayu
Hamsan, Hazwanee
Tan, Eugenie Sin Sing
Mercury contamination in facial skin lightening creams and its health risks to user
author_facet Ho, Yu Bin
Abdullah, Nor Hidayu
Hamsan, Hazwanee
Tan, Eugenie Sin Sing
author_sort Ho, Yu Bin
title Mercury contamination in facial skin lightening creams and its health risks to user
title_short Mercury contamination in facial skin lightening creams and its health risks to user
title_full Mercury contamination in facial skin lightening creams and its health risks to user
title_fullStr Mercury contamination in facial skin lightening creams and its health risks to user
title_full_unstemmed Mercury contamination in facial skin lightening creams and its health risks to user
title_sort mercury contamination in facial skin lightening creams and its health risks to user
publisher Academic Press
publishDate 2017
url http://psasir.upm.edu.my/id/eprint/62393/1/Mercury%20contamination%20in%20facial%20skin%20lightening%20creams%20and%20its%20health%20risks%20to%20user.pdf
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score 13.4562235

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