Cytotoxicity of SRJ23 and its derivatives, expression and SRJ23 binding of KRas G12V oncoprotein
Oncogenic KRas signaling is often associated with a poor prognosis of pancreatic cancer. Effort to target oncogenic KRas signaling persists for years but without much success due to its „undruggable‟ property. In recent years, several small-molecule KRas inhibitors such as SRJ23 were developed to in...
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| Format: | Thèse |
| Langue: | English |
| Publié: |
2017
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| Accès en ligne: | http://psasir.upm.edu.my/id/eprint/68578/1/FPSK%28M%29%202018%2013%20IR.pdf |
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