Identifying common mutations in colorectal cancer using a 7-gene panel by next generation sequencing

Introduction: Colorectal cancer (CRC) arises from the cumulative effects of genetic and epigenetic alterations. Cur-rent treatment of metastatic CRC relies on combination of chemotherapy and targeted therapies such as anti-EGFR therapies. The success of targeted therapies relies on the detection of...

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Main Authors: Chai, Boon Lee, Yip, Wai Kien, Mohd Dusa, Noraini, Mohtarrudin, Norhafizah, Seow, Heng Fong
格式: Article
语言:English
出版: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019
在线阅读:http://psasir.upm.edu.my/id/eprint/75577/1/2019100109012514_MJMHS_0054.pdf
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