Ts1Cje mouse model for Down syndrome exhibits motor function deficit; the potential role of MRFS and peripheral nervous system

Introduction: Down syndrome (DS) is a chromosomal abnormality caused by presence of extra-copy of human chromosome 21. Motor dysfunction due to hypotonia is commonly seen in DS individuals and its etiology is still unknown. In this study, we employed the Ts1Cje, a mouse model for DS to investigate t...

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Bibliographic Details
Main Authors: Bala, Usman, Othman, Fauziah, Lai, Mei I., Ling, King Hwa, Cheah, Pike See
Format: Conference or Workshop Item
Published: 2015
Online Access:http://psasir.upm.edu.my/id/eprint/75605/1/Ts1Cje%20mouse%20model%20for%20Down%20syndrome%20exhibits%20motor%20function%20deficit%3B%20the%20potential%20role%20of%20MRFS%20and%20peripheral%20nervous%20system.pdf