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Occurrence and potential human health risk of pharmaceutical residues in drinking water from Putrajaya (Malaysia)

Occurrence of pharmaceutical residues in drinking water has been widely reported in countries that have registered steady economic growth. This can exert concerns among the general consumers, prompting them to explore the potential human health risks associated with continuous exposure to pharmaceut...

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Hauptverfasser: Praveena, Sarva Mangala, Mohd Rashid, Maizatul Zahirah, Mohd Nasir, Fauzan Adzima, Yee, Wee Sze, Aris, Ahmad Zaharin
Format: Artikel
Sprache:English
Veröffentlicht: Academic Press 2019
Online Zugang:http://psasir.upm.edu.my/id/eprint/81523/1/Occurrence%20and%20potential%20human%20health%20risk%20of%20pharmaceutical%20residues%20in%20drinking%20water%20from%20Putrajaya%20%28Malaysia%29.pdf
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spelling oai:psasir.upm.edu.my:81523 http://psasir.upm.edu.my/id/eprint/81523/ Occurrence and potential human health risk of pharmaceutical residues in drinking water from Putrajaya (Malaysia) Praveena, Sarva Mangala Mohd Rashid, Maizatul Zahirah Mohd Nasir, Fauzan Adzima Yee, Wee Sze Aris, Ahmad Zaharin Occurrence of pharmaceutical residues in drinking water has been widely reported in countries that have registered steady economic growth. This can exert concerns among the general consumers, prompting them to explore the potential human health risks associated with continuous exposure to pharmaceuticals. However, such an occurrence is rarely reported in developing or under-developed countries. To give more contexts, this study looked at the presence of nine pharmaceutical residues in drinking water (amoxicillin, caffeine, chloramphenicol, ciprofloxacin, dexamethasone, diclofenac, nitrofurazone, sulfamethoxazole, and triclosan) at Putrajaya residential area in Malaysia. Additionally, the potential health risks associated with contaminated drinking water were investigated. This study has found the presence of pharmaceutical residue concentrations up to 0.38 ng/L, with the highest concentration of caffeine (0.38 ng/L) and the lowest concentration of diclofenac (0.14 ng/L). In comparison, all the nine pharmaceutical residues were substantially lower than previously reported studies. In general, Hazard Quotient (HQ) values indicated that low potential health hazards were present for all age groups. Nevertheless, quantitative occurrences of pharmaceutical residues in drinking water will help guide future toxicological studies to examine other chronic effects, while canvassing for proper framework to look into the water risk management and regulation in Malaysia. Academic Press 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/81523/1/Occurrence%20and%20potential%20human%20health%20risk%20of%20pharmaceutical%20residues%20in%20drinking%20water%20from%20Putrajaya%20%28Malaysia%29.pdf Praveena, Sarva Mangala and Mohd Rashid, Maizatul Zahirah and Mohd Nasir, Fauzan Adzima and Yee, Wee Sze and Aris, Ahmad Zaharin (2019) Occurrence and potential human health risk of pharmaceutical residues in drinking water from Putrajaya (Malaysia). Ecotoxicology and Environmental Safety, 180. pp. 549-556. ISSN 0147-6513; ESSN: 1090-2414 https://pubmed.ncbi.nlm.nih.gov/31128553/ 10.1016/j.ecoenv.2019.05.051
institution UPM IR
collection UPM IR
language English
description Occurrence of pharmaceutical residues in drinking water has been widely reported in countries that have registered steady economic growth. This can exert concerns among the general consumers, prompting them to explore the potential human health risks associated with continuous exposure to pharmaceuticals. However, such an occurrence is rarely reported in developing or under-developed countries. To give more contexts, this study looked at the presence of nine pharmaceutical residues in drinking water (amoxicillin, caffeine, chloramphenicol, ciprofloxacin, dexamethasone, diclofenac, nitrofurazone, sulfamethoxazole, and triclosan) at Putrajaya residential area in Malaysia. Additionally, the potential health risks associated with contaminated drinking water were investigated. This study has found the presence of pharmaceutical residue concentrations up to 0.38 ng/L, with the highest concentration of caffeine (0.38 ng/L) and the lowest concentration of diclofenac (0.14 ng/L). In comparison, all the nine pharmaceutical residues were substantially lower than previously reported studies. In general, Hazard Quotient (HQ) values indicated that low potential health hazards were present for all age groups. Nevertheless, quantitative occurrences of pharmaceutical residues in drinking water will help guide future toxicological studies to examine other chronic effects, while canvassing for proper framework to look into the water risk management and regulation in Malaysia.
format Article
author Praveena, Sarva Mangala
Mohd Rashid, Maizatul Zahirah
Mohd Nasir, Fauzan Adzima
Yee, Wee Sze
Aris, Ahmad Zaharin
spellingShingle Praveena, Sarva Mangala
Mohd Rashid, Maizatul Zahirah
Mohd Nasir, Fauzan Adzima
Yee, Wee Sze
Aris, Ahmad Zaharin
Occurrence and potential human health risk of pharmaceutical residues in drinking water from Putrajaya (Malaysia)
author_facet Praveena, Sarva Mangala
Mohd Rashid, Maizatul Zahirah
Mohd Nasir, Fauzan Adzima
Yee, Wee Sze
Aris, Ahmad Zaharin
author_sort Praveena, Sarva Mangala
title Occurrence and potential human health risk of pharmaceutical residues in drinking water from Putrajaya (Malaysia)
title_short Occurrence and potential human health risk of pharmaceutical residues in drinking water from Putrajaya (Malaysia)
title_full Occurrence and potential human health risk of pharmaceutical residues in drinking water from Putrajaya (Malaysia)
title_fullStr Occurrence and potential human health risk of pharmaceutical residues in drinking water from Putrajaya (Malaysia)
title_full_unstemmed Occurrence and potential human health risk of pharmaceutical residues in drinking water from Putrajaya (Malaysia)
title_sort occurrence and potential human health risk of pharmaceutical residues in drinking water from putrajaya (malaysia)
publisher Academic Press
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/81523/1/Occurrence%20and%20potential%20human%20health%20risk%20of%20pharmaceutical%20residues%20in%20drinking%20water%20from%20Putrajaya%20%28Malaysia%29.pdf
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score 13.4562235

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