CRISPR-Cas knockout of miR21 reduces glioma growth

by Nieland, Lisa, Solinge, Thomas S. van, Cheah, Pike See, Morsett, Liza M., Khoury, Joseph El, Rissman, Joseph I., Kleinstiver, Benjamin P., Broekman, Marike L. D., Breakefield, Xandra O., Abels, Erik R.
Published 2022

Long-term therapeutic efficacy of intravenous AAV-mediated hamartin replacement in mouse model of tuberous sclerosis type 1

by Prabhakar, Shilpa, Cheah, Pike See, Zhang, Xuan, Zinter, Max, Gianatasio, Maria, Hudry, Eloise, Bronson, Roderick T, Kwiatkowski, David J, Rachamimov, Anat Stemmer, Maguire, Casey A, Sena-Esteves, Miguel, Tannous, Bakhos A, Breakefield, Xandra O
Published 2019

Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells

by Lucero, Rocco, Zappulli, Valentina, Sammarco, Alessandro, Murillo, Oscar D, Cheah, Pike See, Srinivasan, Srimeenakshi, Tai, Eric, Ting, David T., Wei, Zhiyun, Roth, Matthew E., Laurent, Louise C., Krichevsky, Anna M., Breakefield, Xandra O, Milosavljevic, Aleksandar
Published 2020

Glioblastoma-associated microglia reprogramming is mediated by functional transfer of extracellular miR-21

by Abels, Erik R., Maas, Sybren L. N., Nieland, Lisa, Wei, Zhiyun, Cheah, Pike See, Tai, Eric, Kolsteeg, Christy-Joy, Dusoswa, Sophie A., Ting, David T., Hickman, Suzanne, El Khoury, Joseph, Krichevsky, Anna M., Broekman, Marike L. D., Breakefield, Xandra O.
Published 2019

Mutant allele-specific CRISPR disruption in DYT1 dystonia fibroblasts restores cell function

by Cruz, Lilian, Bence, György, Cheah, Pike See, Kleinstiver, Benjamin P., Eimer, William A., Garcia, Sara P., Sharma, Nutan, Ozelius, Laurie J., Cristopher, Bragg D., Joung, Keith J., Norberto de Souza, Osmar, Macedo Timmers, Luis Fernando Saraiva, Breakefield, Xandra O.
Published 2020

Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2

by Prabhakar, Shilpa, Beauchamp, Roberta L., Cheah, Pike See, Yoshinaga, Akiko, Haidar, Edwina Abou, Lule, Sevda, Mani, Gayathri, Maalouf, Katia, Stemmer-Rachamimov, Anat, Jung, David H., Welling, D. Bradley, Giovannini, Marco, Plotkin, Scott R., Maguire, Casey A., Ramesh, Vijaya, Breakefield, Xandra O.
Published 2022

Methods for systematic identification of membrane proteins for specific capture of cancer-derived extracellular vesicles

by Zaborowsk, Mikołaj Piotr, Lee, Kyungheon, Na, Young Jeong, Sammarco, Alessandro, Zhang, Xuan, Iwanicki, Marcin, Cheah, Pike See, Lin, Hsing-Ying, Zinter, Max, Chou, Chung-Yu, Fulci, Giulia, Tannous, Bakhos A., Lai, Charles Pin-Kuang, Birrer, Michael J., Weissleder, Ralph, Lee, Hakho, Breakefield, Xandra O.
Published 2019