Detection of active site conformation changes of gamma-secretase, a key enzyme associated with Alzheimer disease, with small molecules

by Gertsik, Natalya, Li, Yue Ming, Chau, De Ming
Published 2016

γ-secretase inhibitors and modulators induce distinct conformational changes in the active sites of γ-secretase and signal peptide peptidase

by Gertsik, Natalya, Chau, De Ming, Li, Yue Ming
Published 2015

Expression profiling of notch signalling pathway and gamma-secretase activity in the brain of Ts1Cje mouse model of down syndrome

by Md Yusof, Hadri Hadi, Lee, Han Chung, Mohamed Seth, Eryse Amira, Wu, Xiangzhong, Hewitt, Chelsee A., Scott, Hamish S., Cheah, Pike See, Li, Yue Ming, Chau, De Ming, Ling, King Hwa
Published 2019