DNA repair and cancer : from bench to clinic /
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| Other Authors: | , |
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| Format: | Book |
| Language: | English |
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Boca Raton :
Taylor & Francis,
2013.
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Table of Contents:
- Overview of DNA repair pathways / Deborah L. Croteau and Vilhelm A. Bohr
- Longevity assurance by genome maintenance / Paul Hasty, Yousin Suh and Jan Vijg
- Genetic instability of cancer : biological predictions and clinical implications / Robert A. Beckman
- Radiation induced DNA damage, repair, and therapeutics / Lynn Harrison
- Chemotherapeutic alkylating agents in cancer treatment / Tracey D. Bradshaw
- O6-methylguanine-DNA methyltransferase (MGMT) in cancer protection and therapy / Bernd Kaina and Markus Christmann
- DNA mismatch repair : it's role in human carcinogenesis and as a predictive and/or prognostic biomarker for cancer therapy / Timothy J. Kinsella
- DNA base excision repair therapeutics : summary of targets with a focus on APE1 / Melissa L. Fishel, Carlo Vascotto and Mark R. Kelley
- Nucleotide excision repair : DNA repair capacity variability and cancer susceptibility / Li-E Wang and Qingyi Wei
- Fanconi anemia, interstrand cross-link repair, and cancer / Taraswi Banerjee, Sanjay Kumar Bharti and Robert M. Brosh, Jr
- Functions of translesion DNA polymerases : implications for cancer risk and opportunities as therapeutic targets / Kinrin Yamanaka and R. Stephen Lloyd
- P53 in DNA damage, repair and cancer therapeutics / Aditi Gurkar, Kiki Chu and Sam W. Lee
- ATM/ATR cell cycle checkpoints : mechanisms and manipulation in cancer therapy / Marie Fernet, Sara Chiker and Janet Hall
- The BRCA1-BRCA2 pathway of homologous recombination and the opportunity for synthetic lethal approaches to cancer therapy / Laura J. Eccles ... [et al.]
- PARP and PARP inhibitor therapeutics / Nicola J. Curtin
- Tumor genetics and personalized medicine / Mary Ellen Urick and Daphne W. Bell
- The tumor microenvironment and DNA repair : implications for cancer progression and treatment / Norman Chan, Shaqil Kassam and Robert G. Bristow
- Early phase clinical trials using DNA repair inhibitors : lessons learnt / Miranda Payne and Mark Middleton.