Structure-based Drug Discovery

Discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission. Structure-based drug discovery methods have been transformed in the last 5-10 years and are now having a major impact on the discovery of new drugs. Some of...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Jhoti, Harren. (Editor, http://id.loc.gov/vocabulary/relators/edt), Leach, Andrew R. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Format: Electronic eBook
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2007.
Edition:1st ed. 2007.
Subjects:
Online Access:https://doi.org/10.1007/1-4020-4407-0
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Table of Contents:
  • Five Years of Increasing Structural Biology Throughput - A Retrospective Analysis
  • Protein Production for Structural Genomics - Strategies for the Next Phase
  • to Fragment Screening
  • Fragment-Based NMR Screening in Lead Discovery
  • Fragment-Based Screening by X-ray Crystallography
  • Scaffold-Based Drug Discovery
  • Biophysical Methods
  • Illustration of Current Challenges in Molecular Docking
  • Scoring Functions.